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Terbinafine HCL api terbinafine intermeidate cas 78628-80-5 

  Category : Chemicals->Pharmaceutical->pharmaceutical

     
Terbinafine HCL api terbinafine intermeidate cas 78628-80-5
       

  Product Specification
 
  Country  CN

 

    Product Detail
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Product: Terbinafine HCL
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CAS NO.: 78628-80-5
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Standard: Bp<span>,</span><span>usp</span>
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Molecular Formula: C21H26ClN
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Molecular Weight: 327.89
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Description: Off-white or white crystal or crystalline powder
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Package: 25KG/drums
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Application: Antifungal
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Chemical names, synonyms: lamosil, Terbinafine hdyrochloride, Brican, Bricar, Bricaril, Bricyn, KWD 2019, Terbutanline, Tebinaceil
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Minimum purity: 99%
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<img src="http://i.bosscdn.com/product/52/0a/e4/aa663a75cf700a90eb8d761c34.gif" title="Terbinafine HCL 78628-80-5" alt="Terbinafine HCL 78628-80-5" />
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Terbinafine hydrochloride is a kind of broad-spectrum dermatologist allyl amine antifungal drugs. It has a significant effect on all kinds of tinea diseases , including fungus, trichophyton, ringworm of the body, tinea, tinea versicolor and onychomycosis caused by dermophyte. It can also be used for bronchial asthma, asthmatic bronchitis and emphysema, etc. Terbinafine hydrochloride is a synthetic allylamine antifungal. It is used to treat dermatophyte infections of the toenail/fingernail, ringworm and jock itch. It is used in adsorption, partition and stability studies.
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Mode of Action: Inhibits squalene epoxidase, preventing biosynthesis of ergosterol.
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Antimicrobial spectrum: Antifungal and antimycotic. Fungicidal against dermatopytes and some yeasts; fungistatic against&nbsp;Candida albicans.
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Terbinafine inhibits squalene monooxygenase thereby blocking the biosynthesis of ergosterol, which is an essential component of fungal cell membranes. The inhibition of squalene monooxygenase also results in the accumulation of squalene. Terbinafine hydrochloride is highly lipophilic and tends to accumulate in skin, nails, and fatty tissues[1]. It is antifungal and antimycotic. It is fungicidal against dermatopytes and some yeasts and is fungistatic against&nbsp;Candida albicans.
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</p>pharmachemm.com

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