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antifungal imidazole cas 65277-42-1 

  Category : Chemicals->Pharmaceutical->pharmaceutical

     
antifungal imidazole cas 65277-42-1
       

  Product Specification
 
  Country  CN

 

    Product Detail
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Chemical&nbsp;Name: Ketoconazole
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fungarest
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fungoral
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ketoconazol
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ketoderm
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ketoisdin
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Molecular&nbsp;Formula: C26H28Cl2N4O4<br />
Formula&nbsp;Weight: 531.43<br />
CAS&nbsp;No.: 65277-42-1
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<img src="http://i.bosscdn.com/product/af/42/8f/57f7b62c09ee84c2f117cf32f2.gif" title="65277-42-1" alt="65277-42-1" width="200" height="109" /><br />
Water&nbsp;Solubility:&nbsp;Soluble&nbsp;in&nbsp;DMSO,&nbsp;ethanol,&nbsp;chloroform,&nbsp;water,&nbsp;and&nbsp;methanol.<br />
Ketoconazole&nbsp;is&nbsp;used&nbsp;to&nbsp;treat&nbsp;certain&nbsp;serious&nbsp;fungal&nbsp;infections&nbsp;in&nbsp;the&nbsp;body.&nbsp;Ketoconazole&nbsp;belongs&nbsp;to&nbsp;the&nbsp;class&nbsp;of&nbsp;drugs&nbsp;called&nbsp;azole&nbsp;antifungals.&nbsp;It&nbsp;works&nbsp;by&nbsp;stopping&nbsp;the&nbsp;growth&nbsp;of&nbsp;the&nbsp;fungus.<br />
Ketoconazole&nbsp;is&nbsp;a&nbsp;broad-spectrum&nbsp;antifungal&nbsp;imidazole&nbsp;with&nbsp;commercially&nbsp;available&nbsp;product&nbsp;being&nbsp;under&nbsp;the&nbsp;trade&nbsp;name&nbsp;of&nbsp;Jindakening,&nbsp;Meikangling&nbsp;and&nbsp;keNing.&nbsp;It&nbsp;interferes&nbsp;with&nbsp;the&nbsp;activity&nbsp;of&nbsp;fungal&nbsp;cytochrome&nbsp;P-450&nbsp;with&nbsp;a&nbsp;high&nbsp;selectivity,&nbsp;thus&nbsp;inhibiting&nbsp;the&nbsp;biosynthesis&nbsp;of&nbsp;ergosterol&nbsp;in&nbsp;fungal&nbsp;cell&nbsp;membrane.&nbsp;It&nbsp;is&nbsp;effective&nbsp;in&nbsp;treating&nbsp;both&nbsp;shallow,&nbsp;deep&nbsp;fungal&nbsp;infections&nbsp;and&nbsp;can&nbsp;inhibit&nbsp;both&nbsp;fungal&nbsp;growth&nbsp;and&nbsp;the&nbsp;transition&nbsp;from&nbsp;spores&nbsp;to&nbsp;mycelium&nbsp;to&nbsp;prevent&nbsp;the&nbsp;further&nbsp;infection.&nbsp;<br />
Ketoconazole&nbsp;should&nbsp;not&nbsp;be&nbsp;used&nbsp;to&nbsp;treat&nbsp;fungal&nbsp;infections&nbsp;on&nbsp;the&nbsp;skin&nbsp;and&nbsp;nails&nbsp;due&nbsp;to&nbsp;the&nbsp;risk&nbsp;of&nbsp;serious&nbsp;side&nbsp;effects&nbsp;and&nbsp;drug&nbsp;interactions.&nbsp;
</p>pharmachemm.com

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