Sign In Join Help
 
JinanJianfengChemicalCo.,Ltd.

 
 
Recommended Results 
 
Crizotinib intermediate cas 877399-00-3 

  Category : Chemicals->active pharmaceutical ingredient

     
Crizotinib intermediate cas 877399-00-3
       

  Product Specification
 
  Country  CN

 

    Product Detail
  <p class="MsoNormal">
Chemical&nbsp;Name: (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine<br />
Molecular&nbsp;Formula: C13H10BrCl2FN2O<br />
Formula&nbsp;Weight: 380<br />
CAS&nbsp;No.: 877399-00-3
</p>
<p class="MsoNormal">
<img src="http://i.bosscdn.com/product/c6/10/ad/663afa7786dee0a22d5b39b642.gif" title="877399-00-3" alt="877399-00-3" />
</p>
<p class="MsoNormal">
<br />
Chemical&nbsp;Name: Crizotinib<br />
Molecular&nbsp;Formula: C21H22Cl2FN5O<br />
Formula&nbsp;Weight: 450.343<br />
CAS&nbsp;No.: 877399-52-5
</p>
<p class="MsoNormal">
<img src="http://i.bosscdn.com/product/25/2e/7d/b78b53c86f277dde05a26f390c.gif" width="200" height="110" title="877399-52-5" alt="877399-52-5" />
</p>
<p class="MsoNormal">
<br />
Crizotinib&nbsp;is&nbsp;an&nbsp;oral&nbsp;receptor&nbsp;tyrosine&nbsp;kinase&nbsp;inhibitor.&nbsp;The&nbsp;molecular&nbsp;formula&nbsp;for&nbsp;crizotinib&nbsp;is&nbsp;C21H22Cl2FN5O.&nbsp;The&nbsp;molecular&nbsp;weight&nbsp;is&nbsp;450.34&nbsp;Daltons<br />
Potent&nbsp;inhibitor&nbsp;of&nbsp;c-MET&nbsp;and&nbsp;anaplastic&nbsp;lymphoma&nbsp;kinase&nbsp;(ALK)&nbsp;(cell&nbsp;IC50&nbsp;values&nbsp;are&nbsp;8.0&nbsp;and&nbsp;20&nbsp;nM&nbsp;respectively).&nbsp;Selective&nbsp;for&nbsp;c-MET&nbsp;and&nbsp;ALK&nbsp;against&nbsp;&gt;120&nbsp;different&nbsp;kinases.&nbsp;Displays&nbsp;antitumor&nbsp;efficacy&nbsp;in&nbsp;multiple&nbsp;tumor&nbsp;models;&nbsp;inhibits&nbsp;c-MET-dependent&nbsp;proliferation,&nbsp;migration&nbsp;and&nbsp;invasion&nbsp;of&nbsp;human&nbsp;tumor&nbsp;cells&nbsp;in&nbsp;vitro.&nbsp;Orally&nbsp;bioavailable.
</p>pharmachemm.com

  More Products from this Supplier
 
Olopatadine HCL intermediate cas 55453-87-7

Olopatadine HCL intermediate cas 55453-87-7
lurasidone intermediate cas 87691-87-0

lurasidone intermediate cas 87691-87-0
lurasidone intermediate cas 14805-29-9

lurasidone intermediate cas 14805-29-9
Apixaban intermeidate cas 536759-91-8

Apixaban intermeidate cas 536759-91-8
 
   


[ Back Products Catalog ]

Commerce Member:
Please log in your ID and password, we will later fill in relating info.
 
ID: Password: Remember my ID on this computer
Complete this form below to send out your enquiries.
All enquiries will be automatically sent to the company you want to develop.
Subject
Content (Don't input Company Name, E-Mail, Phone Number, Fax Number, and URL)
   

 


Company Profile:
* Company Name
*E-mail
*Country
*Contact Person
URL
*Phone
 - -
Fax
 - -
*Postal code
*City
*Street Address
*Business Nature
 Distributor   Exporter Importer Manufacturer
Whole Sale Retailer  Reseller Retrofitter User
Others, please specify:
*Security Code
Enter the security code.


Site Map l   Privacy Policy l Company Profile l Corporate Proposal l Contact Us l Help l Advertise With Us l  World Trade Link
    .