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Liranafate api Liranafate intermediate CAS 88678-31-3 

  Category : Chemicals->Pharmaceutical->pharmaceutical

     
Liranafate api Liranafate intermediate CAS 88678-31-3
       

  Product Specification
 
  Country  CN

 

    Product Detail
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Product: LIRANAFATE
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CAS NO.: 88678-31-3
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Standard: CP
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Molecular Formula: C18H20N2O2S
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Molecular Weight: 328.43
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Description: Off-white or white crystal or crystalline powder
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Package : 25KG/drums
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Application: Antifungal
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Chemical names, synonyms: M-732, liranaftate, Lipopeptideacetate
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Minimum purity: 99%
</p>
<p class="MsoNormal">
<img src="http://i.bosscdn.com/product/9e/4a/2d/27df176b4bf5729cc67ece11d8.gif" title="Liranafate 88678-31-3" alt="Liranafate 88678-31-3" />
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Chemical&nbsp;medicine/antibacterial&nbsp;drug<br />
Shelf&nbsp;life 2&nbsp;years<br />
Usage&nbsp;anti-fungal&nbsp;drug.<br />
Storage stored&nbsp;in&nbsp;a&nbsp;well-closed&nbsp;container&nbsp;at&nbsp;low&nbsp;temperature,&nbsp;keep&nbsp;away&nbsp;from&nbsp;moisture,&nbsp;heat&nbsp;and&nbsp;light.<br />
Liranaftate&nbsp;is&nbsp;a&nbsp;new&nbsp;king&nbsp;of&nbsp;third-generation&nbsp;dithiocarbamate&nbsp;antifungals&nbsp;,&nbsp;it&nbsp;is&nbsp;a&nbsp;new&nbsp;kind&nbsp;of&nbsp;the&nbsp;third&nbsp;category&nbsp;of&nbsp;chemicals,it&nbsp;belongs&nbsp;to&nbsp;squalene&nbsp;cyclooxygenase&nbsp;inhibitors,&nbsp;by&nbsp;inhibiting&nbsp;the&nbsp;fungal&nbsp;cell&nbsp;membrane&nbsp;squalene&nbsp;epoxidation&nbsp;reaction&nbsp;,&nbsp;it&nbsp;hinders&nbsp;the&nbsp;synthesis&nbsp;of&nbsp;ergosterol&nbsp;which&nbsp;is&nbsp;a&nbsp;constituent&nbsp;of&nbsp;cell&nbsp;membranes&nbsp;,it&nbsp;plays&nbsp;the&nbsp;role&nbsp;of&nbsp;anti-fungal,its&nbsp;anti-fungal&nbsp;activity&nbsp;is&nbsp;8&nbsp;times&nbsp;of&nbsp;tolnaftate,&nbsp;and&nbsp;its&nbsp;dermatophytes&nbsp;effect&nbsp;is&nbsp;better&nbsp;than&nbsp;clotrimazole.&nbsp;It&nbsp;has&nbsp;a&nbsp;strong&nbsp;anti-fungal&nbsp;effect&nbsp;on&nbsp;skin&nbsp;filamentous&nbsp;fungi&nbsp;(Trichophyton,Microsporon,&nbsp;Epidermophyton)&nbsp;,&nbsp;it&nbsp;also&nbsp;shows&nbsp;antifungal&nbsp;activity&nbsp;on&nbsp;other&nbsp;filamentous&nbsp;fungi,&nbsp;dark&nbsp;fungi,&nbsp;dimorphic.It&nbsp;is&nbsp;useful&nbsp;in&nbsp;the&nbsp;treatment&nbsp;of&nbsp;tinea&nbsp;capitis,&nbsp;ringworm,&nbsp;athlete's&nbsp;foot,&nbsp;tinea&nbsp;pedis,&nbsp;onychomycosis,&nbsp;tinea,&nbsp;jock&nbsp;itch,&nbsp;tinea&nbsp;versicolor&nbsp;and&nbsp;vulvovaginal&nbsp;candidiasis.
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</p>pharmachemm.com

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