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JinanJianfengChemicalCo.,Ltd.

 
 
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Ibrutinib impurity intermediate cas 330792-70-6 

  Category : Chemicals->active pharmaceutical ingredient

     
Ibrutinib impurity intermediate cas 330792-70-6
       

  Product Specification
 
  Country  CN

 

    Product Detail
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Chemical&nbsp;Name: 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile<br />
Molecular&nbsp;Formula: C16H12N4O<br />
Formula&nbsp;Weight: 276.29268<br />
CAS&nbsp;No.: 330792-70-6
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Solution&nbsp;in&nbsp;Dulbecco′s&nbsp;Modified&nbsp;Eagle′s&nbsp;Medium&nbsp;with&nbsp;10%&nbsp;fetal&nbsp;calf&nbsp;serum&nbsp;and&nbsp;15&nbsp;mM&nbsp;sodium&nbsp;azide.<br />
Ibrutinib&nbsp;(USAN,[1]&nbsp;also&nbsp;known&nbsp;as&nbsp;PCI-32765&nbsp;and&nbsp;marketed&nbsp;under&nbsp;the&nbsp;name&nbsp;Imbruvica)&nbsp;is&nbsp;an&nbsp;anticancer&nbsp;drug&nbsp;targeting&nbsp;B-cell&nbsp;malignancies.Ibrutinib is a kind of Bruton tyrosine kinase (BTK) inhibitor, it could be used for the treatment of chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). MCL and CLL are belonged to the B-cell non-Hodgkin's lymphoma, which is difficult to cure and easy to recurrent. Common chemical immunotherapy does not have the targeting, often occurs 3 or 4 adverse reactions.
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