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Prilocaine base api and intermediate cas 721-50-6 

  Category : Chemicals->Pharmaceutical->pharmaceutical

     
Prilocaine base api and intermediate cas 721-50-6
       

  Product Specification
 
  Country  CN

 

    Product Detail
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Product: Prilocaine and Intermediates&nbsp;
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CAS NO.: 721-50-6
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Standard: BP,CP,USP
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Molecular Formula: C13H20N2O
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Molecular Weight: 220.31
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Description: White crystal or crystalline powder
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Package: 25KG/drums
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Chemical names, synonyms: astra1512, astra1515, Citanest, L 67, l67
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Minimum purity: 99%
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<img src="http://i.bosscdn.com/product/61/2f/54/c02b92906ea6aa0f793e761f27.gif" title="Prilocaine and Intermediates 721-50-6" alt="Prilocaine and Intermediates 721-50-6" />
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It is a kind of needle-like crystals with the melting point being 37-38 ℃ and the boiling point being 159-162 ℃ (0.133kPa), and refractive index (nD20) being 1.5299. &nbsp;The Melting point is 167-168 ℃. It is soluble in water and ethanol, slightly soluble in chloroform. It has sour taste and bitter taste and is odorless.
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Topological Polar Surface Area 41.1 A^2
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Monoisotopic Mass 220.158 g/mol
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Exact Mass 220.158 g/mol
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It is a kind of local anesthetic drug.It is suitable for epidural anesthesia, conduction anesthesia and infiltration anesthesia.
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Prilocaine&nbsp;is a&nbsp;toluidine&nbsp;derivative and intermediate-acting&nbsp;amino amide&nbsp;with local anesthetic property.&nbsp;Prilocaine&nbsp;stabilizes the neuronal membrane by preferential binding to and inhibiting depolarization of the voltage-gated&nbsp;sodium&nbsp;channel. This results in a decrease in membrane permeability and subsequent inhibition of the ionic&nbsp;sodium&nbsp;influx required for the initiation and conduction of impulses.
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</p>pharmachemm.com

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