Configuration-specific Monoclonal Antibody Based RhoA Activation Assay Kit->specialty chemicals

Join

Help

NewEast Biosciences

	Recommended Results

Configuration-specific Monoclonal Antibody Based RhoA Activation Assay Kit

Category :

Biotech->Biotech Supplies->specialty chemicals

Configuration-specific Monoclonal Antibody Based RhoA Activation Assay Kit

Product Specification

Model No:	80601

Country	US
Brand	NewEast
Size	kit
Minimum Order	1

Product Detail

Small GTPases are a super-family of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of RhoA, and the hydrolysis of GTP to GDP renders it inactive.

Currently the activation of RhoA proteins is assayed with the binding of GTP-bound RhoA to the RhoA-binding domain (RBD) of the RhoA effector protein, Rhotekin. This method is based on the observation that the active, GTP-bound RhoA could bind to the RBD of rhotekin. However, the reproducibility of this method is poor. This is partially due to the relatively quick hydrolysis of GTP to GDP during the assay procedure, and the low binding affinity of RBD to RhoA-GTP.

NewEast Biosciences RhoA Activation Assay Kit is based on the configuration-specific monoclonal antibody that specifically recognizes RhoA-GTP, but not RhoA-GDP. Given the high affinity of monoclonal antibodies to their antigens, the activation assay could be performed in a much shorter time. This assay provides the reliable results with consistent reproducibility.

This anti-RhoA-GTP monoclonal antibody can also be used to monitor the activation of RhoA in cells and in tissues by immunohistochemistry.

NewEast Biosciences RhoA Activation Assay Kit provides a simple and fast method to monitor the activation of RhoA. Each kit provides sufficient quantities to perform 20 assays.

More Products from this Supplier

Monoclonal Anti-cAMP Antibody Based Direct cAMP EIA Kit without Acetylation

Rac Activation Assay Kit

Monoclonal Anti-cGMP Antibody Based Direct cGMP EIA Kit without Acetylation

Anti-B-Raf(V600E) Mouse Monoclonal Antibody


[ Back Products Catalog ]

Commerce Member:
Please log in your ID and password, we will later fill in relating info.

ID:

Password:

Remember my ID on this computer


	Complete this form below to send out your enquiries. All enquiries will be automatically sent to the company you want to develop.

	Subject
	Content	(Don't input Company Name, E-Mail, Phone Number, Fax Number, and URL)

Company Profile:

* Company Name

*E-mail

*Country

*Contact Person

URL

*Phone

- -

Fax

- -

*Postal code

*City

*Street Address

*Business Nature

Distributor Exporter Importer Manufacturer
Whole Sale Retailer Reseller Retrofitter User
Others, please specify:

*Security Code


Enter the security code.