Constitutive Knockout ->pharmaceutical

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Creative Animodel, Inc.

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Constitutive Knockout

Category :

Chemicals->Pharmaceutical->pharmaceutical

Product Specification

Model No:	CA003

Country	0
Brand	Creative Animodel

Product Detail

Creative Animodel's high-throughput conventional knockout technology enables us to identify and validate the utility of genomic targets within a living model at an extraordinary scale and speed. With Creative Animodel, you get targeted knockouts generated through proven technologies and comprehensive phenotypic data analyzed across consistent protocols.

Steps

1 : Subcloning and characterization of the locus of interest
2 : Constitutive knockout vector construction (targeting vector)
3 : Homologous recombination in ES cells
4 : Blastocyst injection and chimera generation
5 : Breeding to the F1 and F2 generation

In the past 20 years, Creative Animodel has been focused on offering custom design and generation of knockout mice for research needs. Germline transmission has been achieved for all knockout projects with competitive timelines.

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