Nanjing Essence Fine Chemical CO., Ltd. – Product Catalog : Agriculture and livestocks, Others, agricultural chemical

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niclosamide

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Agriculture and livestocks->Others->agricultural chemical

Product Specification

Size	EC,WP,TECH
Materials	Niclosamide
Packing	According to the requirements of client
Minimum Order	Negotiate
Payment Term	Negotiate

Product Detail

NOMENCLATURE
niclosamide
Common name niclosamide (BSI, E-ISO, (m) F-ISO, BAN, Germany (for veterinary use))
IUPAC name 2',5-dichloro-4'-nitrosalicylanilide
Chemical Abstracts name 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
CAS RN [50-65-7]

niclosamide-olamine
Common name niclosamide-olamine (BSI, E-ISO, (m) F-ISO, BAN); clonitralid (Germany, for public health use)
CAS RN [1420-04-8]

PHYSICAL CHEMISTRY
niclosamide
Mol. wt. 327.1 M.f. C13H8Cl2N2O4 Form Almost colourless crystals. M.p. 230 ºC V.p. <1 mPa (20 ºC) KOW logP = 1 (pH 9.6) Solubility In water 1.6 (pH 6.4), 110 (pH 9.1) (both in mg/l, 20 ºC). Soluble in common organic solvents such as ethanol and diethyl ether. Stability Hydrolysed in aqueous solution, DT50 (20 ºC) c. 7 d (pH 6.9), 18.8 d (pH 13.3). Stable to heat. Decomposes under u.v. irradiation. Hydrolysed by concentrated acid or alkali.

niclosamide-olamine
Mol. wt. 388.2 M.f. C15H15Cl2N3O5 Form Yellow, crystalline solid. M.p. Decomposes at 208 ºC V.p. <<1 mPa (20 °C) Solubility In water 0.1 g/l (20 ºC). In n-hexane, toluene <0.1, dichloromethane 0.015, isopropanol 0.25 (all in g/l, 20 ºC).

APPLICATIONS
Mode of action Molluscicide with respiratory and stomach action. Uses Control of golden apple snail in rice. Control of schistosomiasis and fascioliasis in man by killing fresh-water snails which act as intermediate hosts. Also used for veterinary control of tapeworm infestations. Formulation types EC.

niclosamide
Compatibility Incompatible with acidic materials. Selected tradenames: 'Bayluscide' (EC250) (Bayer) Formulation types WP.

niclosamide-olamine
Selected tradenames: 'Bayluscide' (WP70) (Bayer)

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